Stop guessing.
Start sequencing.

ProxiGene™ is a one-time analysis of 400+ scientifically validated SNPs that reveals how each patient's DNA influences metabolism, cognition, emotional resilience, inflammation, nutrient absorption, and aging — before you write a single protocol. Non-invasive saliva collection. 3-week report turnaround.

400+ BiomarkersNon-Invasive Saliva Test3-Week TurnaroundProtocol Report Included
400+

Scientifically Validated SNPs

3 wks

Report Turnaround

6

Biomarker Categories

100%

Non-Invasive Collection

One-size-fits-all protocols
are becoming obsolete.

Two patients. Same age. Same chief complaint. Same standard protocol. Completely different outcomes. This isn't a coincidence — it's genetics.

Standard peptide protocols are calibrated for a hypothetical average patient. Your actual patient has specific SNP variants that determine how they metabolize peptides, how sensitive their hormone receptors are, how efficiently they process key nutrients, and how robustly they respond to cognitive or metabolic interventions.

ProxiGene™ decodes those variables before you write the first prescription. The result: protocols that are informed by the patient's actual biology — not population averages.

Without ProxiGene™

Standard semaglutide starting dose for all metabolic patients

With ProxiGene™

GLC and LDL/HDL variants inform dose selection and metabolic peptide stack

Without ProxiGene™

Cognitive peptides prescribed based on symptom report alone

With ProxiGene™

COG and FOG markers identify neuroinflammation and neurotransmitter pathway risk before protocol design

Without ProxiGene™

Growth hormone secretagogues selected by general patient profile

With ProxiGene™

TEL, INF, and cellular longevity markers guide GHS selection for longevity protocols

Without ProxiGene™

Nutrient support added by clinical intuition

With ProxiGene™

B9 and B12 SNP variants identify MTHFR-related deficiency risk — specific active forms recommended

Six categories. One comprehensive
genetic picture.

Each category maps to a specific clinical domain — and each finding maps to a specific peptide or supplement intervention recommendation in the report.

01

Cognitive Degeneration

Memory, neuroinflammation, and age-related cognitive decline.

Cognitive Decline Risk (COG)

Example Interventions

Epithalon, Dihexa, GHK-Cu, Semax/Selank peptides; Magnesium L-Threonate, Citicoline

02

Longevity

Inflammatory response regulation, telomerase gene susceptibility (cellular aging), and cellular repair & mitochondrial health.

Inflammatory Response (INF)Telomerase Function (TEL)Cellular Longevity

Example Interventions

Epithalon, MOTS-c, TB-500, Resveratrol & Pterostilbene; Curcumin, Quercetin, NAC

03

Psychological Resilience

Brain fog & neurotransmitter regulation, dopamine/serotonin pathways, generalized anxiety & stress response, cortisol & environmental reactivity.

Brain Fog (FOG)Optimism (OPT)Anxiety Disorder (ANX)Stress Sensitivity (STR)

Example Interventions

Selank, Semax, Oxytocin peptides; Ashwagandha, Magnesium, Valerian Root, Saffron

04

Micronutrient Metabolism

Vitamin B9 (Folate) deficiency risk and Vitamin B12 deficiency risk — both directly influence methylation and peptide efficacy.

Vitamin B9 Folate (B9)Vitamin B12 (B12)

Example Interventions

L-5-MTHF (active folate), Methylcobalamin (active B12); monitor levels annually

05

Metabolism & Energy

LDL/HDL cholesterol regulation, triglyceride metabolism, and blood glucose regulation — the genetic foundation of metabolic protocol selection.

LDL Cholesterol (LDL)HDL Cholesterol (HDL)Triglycerides (TRG)Blood Glucose (GLC)

Example Interventions

MOTS-c, Tesamorelin, AOD-9604, CJC-1295/Ipamorelin; Berberine, Psyllium husk, Chromium

06

Food Sensitivity Response

Lactose intolerance and gluten sensitivity risk — informs dietary context for protocol optimization and supplement selection.

Lactose Intolerance (LAC)Gluten Sensitivity (GLT)

Example Interventions

Dietary modifications and targeted supplementation based on genetic advantage or risk findings

Intervention examples shown are physician-curated protocol suggestions from sample reports. Actual recommendations are patient-specific based on individual genetic findings. All peptides are research-grade for physician-supervised clinical research protocols.

Genetic sequencing laboratory

Precision health begins with your code.
ProxiGene™ is your differentiation.

Not a raw data dump.
A clinical action plan.

The ProxiGene™ report is designed for clinical interpretation — not for patients to read on their own. Every finding is translated into a specific, physician-directed recommendation. You receive a complete protocol guide, not a list of gene variants.

The Genetic Risk Matrix gives you a color-coded snapshot of all 15 biomarker categories at a glance — High, Medium, or Low risk — so you can prioritize the most clinically significant findings before diving into the detail.

01

Gene & SNP Details

Full rsID-level data including specific allele impacts for every marker assessed.

02

Risk & Propensity Scores

Every biomarker rated High / Medium / Low risk with a color-coded Genetic Risk Matrix for fast clinical interpretation.

03

Nutrition & Lifestyle Insights

Evidence-based recommendations tied directly to the patient's specific genetic findings — not population averages.

04

Peptide & Supplement Guidance

Physician-curated protocol suggestions mapped to each risk category. Specific peptides named per finding.

05

Follow-Up Labs

Confirmatory and monitoring lab suggestions to track protocol response and validate genetic risk predictions.

What a real report looks like
for your patient.

Below is an example of the risk categorization and intervention guidance from an actual ProxiGene™ analysis. Every patient receives findings across all six categories — and each finding comes with a specific protocol recommendation.

Cognitive Degeneration

HIGH
  • Cognitive Decline Risk — HIGH

Protocol Guidance

Epithalon, Dihexa, GHK-Cu, Semax/Selank peptides; Magnesium L-Threonate, Citicoline

Psychological Resilience

HIGH
  • Brain Fog — HIGH
  • Anxiety Disorder — HIGH
  • Optimism — MED
  • Stress Sensitivity — MED

Protocol Guidance

Selank, Semax, Oxytocin peptides; Ashwagandha, Magnesium, Valerian Root, Saffron

Metabolism & Energy

HIGH
  • LDL Cholesterol — HIGH
  • Blood Glucose — HIGH
  • HDL Cholesterol — MED
  • Triglycerides — MED

Protocol Guidance

MOTS-c, Tesamorelin, AOD-9604, CJC-1295/Ipamorelin; Berberine, Psyllium husk, Chromium

Longevity

MEDIUM
  • Inflammatory Response — MED
  • Telomerase Function — MED
  • Cellular Longevity — MED

Protocol Guidance

Epithalon, MOTS-c, TB-500, Resveratrol & Pterostilbene; Curcumin, Quercetin, NAC

Micronutrient Metabolism

MEDIUM
  • Vitamin B9 Folate — MED
  • Vitamin B12 — MED

Protocol Guidance

L-5-MTHF (active folate), Methylcobalamin (active B12); monitor levels annually

Food Sensitivity

FAVORABLE
  • Lactose Intolerance — LOW
  • Gluten Sensitivity — MED

Protocol Guidance

Genetic Advantage: Excellent lactose tolerance. Continue dairy for calcium/protein. Monitor gluten response.

Sample findings shown are from an anonymized ProxiGene™ report. Individual patient results will vary. All protocol recommendations are physician-directed. Peptides referenced are research-grade for use in physician-supervised clinical research protocols.

In-office or direct-to-patient.
Your workflow, your choice.

01

Order Kits

Order ProxiGene™ saliva collection kits for in-office use or direct-to-patient shipping. No phlebotomist required.

02

Patient Collects

Non-invasive saliva collection takes minutes. Fully manageable at home — patients mail the kit directly to the lab.

03

CLIA-Certified Analysis

Samples are analyzed at our CLIA-certified lab partner. 400+ scientifically validated SNPs assessed across all 6 categories.

04

Protocol Report

3-week turnaround. Complete Genetic Risk Matrix plus category-by-category peptide and supplement guidance delivered digitally.

ProxiGene™ provides genetic insights to inform protocol development. It is not a diagnostic tool and does not diagnose, treat, or prevent any medical condition. For use by licensed healthcare providers only in the context of physician-supervised clinical programs. © 2025 HealthSpan360 LLC. All rights reserved.

Differentiate your practice with precision genetics.

Prescribe peptide protocols backed by your patient's actual biology. Request ProxiGene™ partner information today.